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Antwerp Centre for Advanced Microscopy
High impact science through systematic and quantitative imaging
Publications
Activation of the Carboxypeptidase U (CPU, TAFIa, CPB2) System in Patients with SARS-CoV-2 Infection Could Contribute to COVID-19 Hypofibrinolytic State and Disease Severity Prognosis.
Claesen K, Sim Y, Bracke A, De Bruyn M, De Hert E, Vliegen G, Hotterbeekx A, Vujkovic A, van Petersen L, De Winter FHR, Brosius I, Theunissen C, van Ierssel S, van Frankenhuijsen M, Vlieghe E, Vercauteren K, Kumar-Singh S, De Meester I, Hendriks D
J Clin Med
2022 Mar 9
Luminescent Human iPSC-Derived Neurospheroids Enable Modeling of Neurotoxicity After Oxygen-glucose Deprivation.
Van Breedam E, Nijak A, Buyle-Huybrecht T, Di Stefano J, Boeren M, Govaerts J, Quarta A, Swartenbroekx T, Jacobs EZ, Menten B, Gijsbers R, Delputte P, Alaerts M, Hassannia B, Loeys B, Berneman Z, Timmermans JP, Jorens PG, Vanden Berghe T, Fransen E, Wouters A, De Vos WH, Ponsaerts P
Neurotherapeutics
2022 Mar 14
Proline-specific peptidase activities (DPP4, PRCP, FAP and PREP) in plasma of hospitalized COVID-19 patients.
Bracke A, De Hert E, De Bruyn M, Claesen K, Vliegen G, Vujkovic A, van Petersen L, De Winter FHR, Hotterbeekx A, Brosius I, Theunissen C, Van Ierssel S, van Frankenhuijsen M, Vlieghe E, Vercauteren K, Van der Veken P, Hendriks D, Kumar-Singh S, De Meester I
Clin Chim Acta
2022 Mar 10
Cellular senescence in neuroblastoma.
Zanotti S, Decaesteker B, Vanhauwaert S, De Wilde B, De Vos WH, Speleman F
Br J Cancer
2022 Feb 23
The cellular response to plasma membrane disruption for nanomaterial delivery.
Houthaeve G, De Smedt SC, Braeckmans K, De Vos WH
Nano Converg
2022 Feb 1
Vasoconstrictor antagonism improves functional and structural vascular alterations and liver damage in rats with early NAFLD.
van der Graaff D, Chotkoe S, De Winter B, De Man J, Casteleyn C, Timmermans JP, Pintelon I, Vonghia L, Kwanten WJ, Francque S
JHEP Rep
2021 Nov 25
Genomic and Phenotypic Characterization of Experimentally Selected Resistant Leishmania donovani Reveals a Role for Dynamin-1-Like Protein in the Mechanism of Resistance to a Novel Antileishmanial Compound.
Hefnawy A, Negreira G, Jara M, Cotton JA, Maes I, D'Haenens E, Imamura H, Cuypers B, Monsieurs P, Mouchtoglou C, De Winter H, Pintelon I, Timmermans JP, Berriman M, Sanders M, Martin J, de Muylder G, Dujardin JC, Sterckx YG, Domagalska MA
mBio
2022 Jan 11
Transient nuclear lamin A/C accretion aids in recovery from vapor nanobubble-induced permeabilisation of the plasma membrane.
Houthaeve G, García-Díaz Barriga G, Stremersch S, De Keersmaecker H, Fraire J, Vandesompele J, Mestdagh P, De Smedt S, Braeckmans K, De Vos WH
Cell Mol Life Sci
2022 Jan 4
Constitutive, Basal, and β-Alanine-Mediated Activation of the Human Mas-Related G Protein-Coupled Receptor D Induces Release of the Inflammatory Cytokine IL-6 and Is Dependent on NF-κB Signaling.
Arora R, Van Theemsche KM, Van Remoortel S, Snyders DJ, Labro AJ, Timmermans JP
Int J Mol Sci
2021 Dec 9
High-LET Carbon and Iron Ions Elicit a Prolonged and Amplified p53 Signaling and Inflammatory Response Compared to low-LET X-Rays in Human Peripheral Blood Mononuclear Cells.
Macaeva E, Tabury K, Michaux A, Janssen A, Averbeck N, Moreels M, De Vos WH, Baatout S, Quintens R
Front Oncol
2021 Nov 23
ATG4B Inhibitor UAMC-2526 Potentiates the Chemotherapeutic Effect of Gemcitabine in a Panc02 Mouse Model of Pancreatic Ductal Adenocarcinoma.
Takhsha FS, Vangestel C, Tanc M, De Bruycker S, Berg M, Pintelon I, Stroobants S, De Meyer GRY, Van Der Veken P, Martinet W
Front Oncol
2021 Nov 18
Blood Cytokine Analysis Suggests That SARS-CoV-2 Infection Results in a Sustained Tumour Promoting Environment in Cancer Patients.
De Winter FHR, Hotterbeekx A, Huizing MT, Konnova A, Fransen E, Jongers B, Jairam RK, Van Averbeke V, Moons P, Roelant E, Le Blon D, Vanden Berghe W, Janssens A, Lybaert W, Croes L, Vulsteke C, Malhotra-Kumar S, Goossens H, Berneman Z, Peeters M, van Dam PA, Kumar-Singh S
Cancers (Basel)
2021 Nov 15
Prediction of biological age by morphological staging of sarcopenia in Caenorhabditis elegans.
Dhondt I, Verschuuren C, Zečić A, Loier T, Braeckman BP, De Vos WH
Dis Model Mech
2021 Nov 30
Maternal Benzophenone Exposure Impairs Hippocampus Development and Cognitive Function in Mouse Offspring.
Cui F, Pan Q, Wang S, Zhao F, Wang R, Zhang T, Song Y, He J, Zhang H, Weng Q, Jin Y, Xia W, Li Y, Yang GY, De Vos WH, Timmermans JP, Xu S, Tang Y, Sheng X
Adv Sci (Weinh)
2021 Oct 28
Photothermal nanofibres enable safe engineering of therapeutic cells.
Xiong R, Hua D, Van Hoeck J, Berdecka D, Léger L, De Munter S, Fraire JC, Raes L, Harizaj A, Sauvage F, Goetgeluk G, Pille M, Aalders J, Belza J, Van Acker T, Bolea-Fernandez E, Si T, Vanhaecke F, De Vos WH, Vandekerckhove B, van Hengel J, Raemdonck K, Huang C, De Smedt SC, Braeckmans K
Nat Nanotechnol
2021 Oct 21
Characterisation of Gel-Forming Mucins Produced In Vivo and In Ex Vivo Conjunctival Explant Cultures.
Van Acker SI, Van den Bogerd B, Van Acker ZP, Vailionytė A, Haagdorens M, Koppen C, Ní Dhubhghaill S, Dartt DA, Pintelon I
Int J Mol Sci
2021 Sep 29
Correction to: High‑throughput Analysis of Synaptic Activity in Electrically Stimulated Neuronal Cultures.
Van Dyck M, Mishra RK, Pestana F, Verstraelen P, Lavreysen H, Pita-Almenar JD, Kashikar ND, De Vos WH
Neuroinformatics
2022 Jul
Assessing the Impact of Flavophospholipol and Virginiamycin Supplementation on the Broiler Microbiota: a Prospective Controlled Intervention Study.
Mysara M, Berkell M, Xavier BB, De Backer S, Lammens C, Hautekiet V, Petkov S, Goossens H, Kumar-Singh S, Malhotra-Kumar S
mSystems
2021 Aug 31
A dynamic mucin mRNA signature associates with COVID-19 disease presentation and severity.
Smet A, Breugelmans T, Michiels J, Lamote K, Arras W, De Man JG, Heyndrickx L, Hauner A, Huizing M, Malhotra-Kumar S, Lammens M, Hotterbeekx A, Kumar-Singh S, Verstraeten A, Loeys B, Verhoeven V, Jacobs R, Dams K, Coenen S, Ariën KK, Jorens PG, De Winter BY
JCI Insight
2021 Oct 8
Comprehensive polar metabolomics and lipidomics profiling discriminates the transformed from the non-transformed state in colon tissue and cell lines.
Rombouts C, De Spiegeleer M, Van Meulebroek L, Vanhaecke L, De Vos WH
Sci Rep
2021 Aug 26
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