Antwerp Centre for Advanced Microscopy

High impact science through systematic and quantitative imaging

Publications

Achaete-Scute-Like 1a Expression Is Essential for the Generation of Correct Proportions of Neuron Subtypes in the Developing Enteric Nervous System of Zebrafish (Danio rerio).

Popowycz N, Uyttebroek L, Timmermans JP, Van Nassauw L

Gastro Hep Adv

2026 May 5

https://doi.org/10.1016/j.gastha.2026.100990

Kv7.2 loss-of-function causes early hyperexcitability and network remodelling.

Dirkx N, Kaji M, De Vriendt E, Carleo G, Miceli F, Asselbergh B, Verstraelen P, Zonnekein N, Carotenuto L, Dang LT, Sommers V, Vlaemynck E, Lagae L, Ceulemans B, De Jonghe P, De Vos WH, Taglialatela M, Weckhuysen S

Brain

2026 Jun 6

https://doi.org/10.1093/brain/awag199

An Adnp frameshift variant disrupts Wnt signalling inducing chromatocytoskeletal defects and autism-related behaviour in male mice.

D'Incal CP, Cappuyns E, Paldi F, van der Lei MB, Annear DJ, Alastruey CM, Sokolova D, Elinck E, De Man K, Konings A, Huyghebaert J, Thys S, Pintelon I, Verschuuren M, Calus E, Van Dam D, De Deyn PP, Nguyen S, Yalcin B, Horii T, Hatada I, Mateiu L, Cavalli G, Pasciuto E, Berghe WV, Kooy RF

EBioMedicine

2026 May 28

https://doi.org/10.1016/j.ebiom.2026.106309

Phenotypic convergence and collateral susceptibility development in Pseudomonas aeruginosa under antibiotic exposure in ICU patients.

van der Schalk TE, Berkell M, Hottebeekx A, Timbermont L, Tabor DE, Lammens C, Recanatini C, Ruzin A, DiGiandomenico A, Jafri H, Chastre J, Esser MT, François B, Bonten MJM, Goossens H, Kluytmans JAJW, Oliver A, Glupczynski Y, Kumar-Singh S, Malhotra-Kumar S, ASPIRE-ICU study team, COMBACTE-MAGNET EVADE study group

NPJ Antimicrob Resist

2026 May 8

https://doi.org/10.1038/s44259-026-00199-3

Expertise is the new infrastructure.

Hernandez-Varas P, Rossi C, Tranfield EM, Bajoghli B, Prats C, De Vos WH, Munck S

J Microsc

2026 May 6

https://doi.org/10.1111/jmi.70103

Unperturbed dye-based imaging of spontaneous synchronized calcium activity in iPSC-derived neuronal cultures.

Dirkx N, Asselbergh B, Verstraelen P, Van Lent J, De Vriendt E, Timmerman V, De Vos WH, Weckhuysen S

iScience

2026 Apr 9

https://doi.org/10.1016/j.isci.2026.115689

Calciprotein particles disrupt autophagy in vascular endothelial cells and smooth muscle cells.

Sharifimoghaddammood N, Pintelon I, De Vos WH, Roth L, Neutel CHG

Atheroscler Plus

2026 Mar 20

https://doi.org/10.1016/j.athplu.2026.100558

Cationic mRNA Lipid Nanoparticles for Ex Vivo NanoCAR-T Cell Engineering.

Harinck L, De Munter S, De Velder M, Ingels J, Berdecka D, Lentacker I, De Vos WH, Vandekerckhove B, Braeckmans K, Raemdonck K

Adv Sci (Weinh)

2026 Mar 24

https://doi.org/10.1002/advs.202521507

Exopolysaccharides of Lactobacillus crispatus mediate key balancing interactions with the vaginal mucosa.

Croatti V, Dricot C, Eilers T, Dillen J, Van Rillaer T, Cauwenberghs E, Van Tente I, Bakelants S, Vandenheuvel D, Allonsius C, Pintelon I, Thys S, Mensah W, Naldi M, Bron PA, Wittouck S, Spacova I, Parolin C, Vitali B, Lebeer S

NPJ Biofilms Microbiomes

2026 Feb 19

https://doi.org/10.1038/s41522-026-00937-5

DRP1 depletion protects NK cells from hypoxia-induced dysfunction.

Verhezen T, Van Den Eynde A, Verstraelen P, Gehrcken L, Palmiotto G, Lau HW, De Vos WH, Van Der Heijden S, Brants L, Melis J, Van Audenaerde J, Rodrigues Fortes F, Le Compte M, Roeyen G, Prenen H, Campillo-Davo D, Lion E, Argüello RJ, Van Laere S, Lardon F, Deben C, Wouters A, Smits E, De Waele J

Redox Rep

2026 Feb 18

https://doi.org/10.1080/13510002.2026.2626181

Immunogenicity, reactogenicity and safety to assess booster vaccinations with BNT162b2 or double-dose mRNA-1273 in adults ≥75 years (EU-COVAT-1-AGED) - final report.

Stemler J, Yeghiazaryan L, Stephan C, Mohn KG, Cox RJ, Carcas-Sansuan AJ, Rodriguez ER, Moltó J, Mitxeltorena IV, Pink I, Welte T, Zablockienė B, Akova M, Bethe U, Grimm S, Salmanton-García J, Jakobs J, Tischmann L, Zarrouk M, Cüppers A, Biehl LM, Grothe J, Mellinghoff SC, Nacov JA, Neuhann JM, Sprute R, Frías-Iniesta J, Negi R, Gaillard C, Saini G, León AG, Mallon PWG, Lammens C, Hotterbeekx A, Loens K, Malhotra-Kumar S, Goossens H, Kumar-Singh S, König F, Posch M, Koehler P, Cornely OA, EU-COVAT-1 AGED study group on behalf of the VACCELERATE Consortium

Int J Infect Dis

2026 Feb 6

https://doi.org/10.1016/j.ijid.2026.108466

SV2A PET Imaging Detects Severity-Dependent Synaptic Changes After Experimental Traumatic Spinal Cord Injury.

Schrauwen C, Halloin N, Van Eetveldt A, Laermans Z, De Vos WH, Jankovski A, Verhoye M, Staelens S, Nicaise C, Bertoglio D

J Nucl Med

2026 Feb 5

https://doi.org/10.2967/jnumed.125.271236

Polydopamine Nanoparticle-Sensitized Photoporation Delivers Macromolecules in Monocytes and Macrophages with Minimal Impact on Cell Homeostasis.

Goemaere I, Harizaj A, De Smedt SC, De Vos WH, Braeckmans K

Small Methods

2026 Jan 18

https://doi.org/10.1002/smtd.202501492

Cytokines, Somatosensory Functioning, and Psychological Distress in Post-Breast Cancer Surgery Pain: A longitudinal study.

De Groote A, Meeus M, Coppens L, Kumar-Singh S, Dams L, Mosselmans J, Tjalma W, De Groef A, Gcam MM

Brain Behav Immun

2026 Jan 13

https://doi.org/10.1016/j.bbi.2026.106281

Engineering Carbon Nitride Quantum Dots via Sulfur Doping for Controlled Reactive Oxygen Species Generation.

Belko N, Maltanava H, Brezhneva N, Tamarov K, Lehto VP, Moilanen JO, Leskinen JTT, Semenov D, Filonenko E, Koshevoy I, Schneidewind J, De Vos WH, Kuzhir P

Glob Chall

2026 Jan 8

https://doi.org/10.1002/gch2.202500447

Low-grade mucosal inflammation in aged senescence-accelerated mouse-prone 8 mice blunts epithelial barrier recovery after dextran sodium sulphate-induced chronic colitis.

Verboven R, Verstraelen P, De Loose N, Ott J, Hanning N, De Winter BY, Timmermans JP, De Vos WH

Biogerontology

2026 Jan 10

https://doi.org/10.1007/s10522-026-10385-5

Maternal and neonatal outcomes after infection with monkeypox virus clade I during pregnancy in DR Congo: a pooled, prospective cohort study.

Vakaniaki EH, Barhishindi I, Mubiala A, Malembaka EB, Braunack-Mayer L, Nganga B, Sabiti Nundu S, Brosius I, Bracke S, Bangwen E, De Vos E, Colebunders R, Ngale M, Kayembe G, Tshongo C, Dilu A, Tshimanga C, Biampata JL, Bugeme PM, Ntamabyaliro N, Kirenga B, Wayengera M, Siewe Fodjo JN, Lupande Mwenebitu D, Rimoin AW, Wawina-Bokalanga T, Vercauteren K, Mukadi-Bamuleka D, Muyembe-Tamfum JJ, Krasemann S, Kindrachuk J, Azman AS, Nussenblatt V, Crozier I, Dodd LE, Tshiani-Mbaya O, MBOTE-SK Consortium, PREGMPOX Consortium, PALM007 Consortium, Uvira Study Group, Low N, Katoto PDMC, Mbala-Kingebeni P, Liesenborghs L

Lancet

2025 Dec 19

https://doi.org/10.1016/S0140-6736(25)02309-8

LRRC59 cooperates with nuclear transporters to restrain the nuclear envelope repair machinery and safeguard genome integrity.

Timmer R, Bellanger A, Peeters S, Kim H, de la Ballina LR, Eikvar S, Arns AJ, Oortgijs E, Sekulić N, De Vos WH, Campsteijn C

Nat Commun

2025 Dec 12

https://doi.org/10.1038/s41467-025-65994-4

A comprehensive longitudinal analysis of the cellular immune response specific to the spike protein in healthcare workers vaccinated against SARS-CoV-2- ORCHESTRA Project.

Ugel S, Gupta A, Spiteri G, Marchetti P, De Sanctis F, Wouters S, Konnova A, Monaco MGL, Carta A, Pezzani MD, Liviero F, Pavanello S, dell'Omo M, Fabiánová E, Bérešová J, Larese Filon F, Mauro M, Verlato G, Bronte V, Kumar-Singh S, Porru S

Front Immunol

2025 Nov 25

https://doi.org/10.3389/fimmu.2025.1707449

Short- and Long-term Humoral Response of Immunosuppressed Children to SARS-CoV-2 BNT162b2 Vaccine.

Tagarro A, Gastesi I, Hotterbeekx A, Aguilera-Alonso D, Konnova A, Gupta A, Salso S, Berkell M, Plata MDC, Domínguez-Rodríguez S, Ballesteros Á, Manzanares Á, Oltra M, Villanueva S, Pinto C, Guillén R, Giaquinto C, Moraleda C, Kumar-Singh S

Pediatr Infect Dis J

2025 Dec 5

https://doi.org/10.1097/INF.0000000000005042

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