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Antwerp Centre for Advanced Microscopy

High impact science through systematic and quantitative imaging

Publications

A Microfluidic In Vitro Three-Dimensional Dynamic Model of the Blood-Brain Barrier to Study the Transmigration of Immune Cells.
Meena M, Vandormael R, De Laere M, Pintelon I, Berneman Z, Watts R, Cools N

Brain Sci

2022 Sep 25

Altered basal forebrain function during whole-brain network activity at pre- and early-plaque stages of Alzheimer's disease in TgF344-AD rats.
van den Berg M, Adhikari MH, Verschuuren M, Pintelon I, Vasilkovska T, Van Audekerke J, Missault S, Heymans L, Ponsaerts P, De Vos WH, Van der Linden A, Keliris GA, Verhoye M

Alzheimers Res Ther

2022 Oct 10

Clinical Impact of Monoclonal Antibodies in the Treatment of High-Risk Patients with SARS-CoV-2 Breakthrough Infections: The ORCHESTRA Prospective Cohort Study.
Savoldi A, Morra M, Castelli A, Mirandola M, Berkell M, Smet M, Konnova A, Rossi E, Cataudella S, De Nardo P, Gentilotti E, Gupta A, Fasan D, Gibbin E, Cioli Puviani F, Hasenauer J, Gusinow R, Tami A, Kumar-Singh S, Malhotra-Kumar S, mAb Orchestra Working Group, Tacconelli E

Biomedicines

2022 Aug 24

Enteric glial cells favor accumulation of anti-inflammatory macrophages during the resolution of muscularis inflammation.
Stakenborg M, Abdurahiman S, De Simone V, Goverse G, Stakenborg N, van Baarle L, Wu Q, Pirottin D, Kim JS, Chappell-Maor L, Pintelon I, Thys S, Pollenus E, Boon L, Van den Steen P, Hao M, Van Ginderachter JA, Boeckxstaens GE, Timmermans JP, Jung S, Marichal T, Ibiza S, Matteoli G

Mucosal Immunol

2022 Sep 7

Subtle vascular and astrocytic changes in the brain of coronavirus disease 2019 (COVID-19) patients.
Rosu GC, Mateescu VO, Simionescu A, Istrate-Ofiteru AM, Curcă GC, Pirici I, Mogoanta L, Mindrila I, Kumar-Singh S, Hostiuc S, Pirici D

Eur J Neurol

2022 Oct 1

The dynamic transcriptome during maturation of biofilms formed by methicillin-resistant Staphylococcus aureus.
Vlaeminck J, Lin Q, Xavier BB, De Backer S, Berkell M, De Greve H, Hernalsteens JP, Kumar-Singh S, Goossens H, Malhotra-Kumar S

Front Microbiol

2022 Jul 28

Identification of healthspan-promoting genes in Caenorhabditis elegans based on a human GWAS study.
Saul N, Dhondt I, Kuokkanen M, Perola M, Verschuuren C, Wouters B, von Chrzanowski H, De Vos WH, Temmerman L, Luyten W, Zečić A, Loier T, Schmitz-Linneweber C, Braeckman BP

Biogerontology

2022 Jun 24

Correction to: Luminescent Human iPSC-Derived Neurospheroids Enable Modeling of Neurotoxicity After Oxygen-glucose Deprivation.
Van Breedam E, Nijak A, Buyle-Huybrecht T, Di Stefano J, Boeren M, Govaerts J, Quarta A, Swartenbroekx T, Z Jacobs E, Menten B, Gijsbers R, Delputte P, Alaerts M, Hassannia B, Loeys B, Berneman Z, Timmermans JP, G Jorens P, Vanden Berghe T, Fransen E, Wouters A, H De Vos W, Ponsaerts P

Neurotherapeutics

2022 Jul

Clinical efficacy of different monoclonal antibody regimens among non-hospitalised patients with mild to moderate COVID-19 at high risk for disease progression: a prospective cohort study.
Savoldi A, Morra M, De Nardo P, Cattelan AM, Mirandola M, Manfrin V, Scotton P, Giordani MT, Brollo L, Panese S, Lanzafame M, Scroccaro G, Berkell M, Lippi G, Konnova A, Smet M, Malhotra-Kumar S, Kumar-Singh S, Tacconelli E, mAb Working Group

Eur J Clin Microbiol Infect Dis

2022 Jun 21

Neuro-immune interactions and the role of Mas-related G protein-coupled receptors in the gastrointestinal tract.
Van Remoortel S, Lambeets L, Timmermans JP

Anat Rec (Hoboken)

2022 Jun 13

Cells infected with human papilloma pseudovirus display nuclear reorganization and heterogenous infection kinetics.
Molenberghs F, Verschuuren M, Barbier M, Bogers JJ, Cools N, Delputte P, Schelhaas M, De Vos WH

Cytometry A

2022 Jun 18

Improved Characteristics of RANKL Immuno-PET Imaging Using Radiolabeled Antibody Fab Fragments.
Dewulf J, Hrynchak I, Geudens S, Pintelon I, Vangestel C, Sereno J, van Dam PA, Abrunhosa AJ, Elvas F, Van den Wyngaert T

Pharmaceutics

2022 Apr 26

Evaluation of the Kinetics of Antibody Response to COVID-19 Vaccine in Solid Organ Transplant Recipients: The Prospective Multicenter ORCHESTRA Cohort.
Giannella M, Righi E, Pascale R, Rinaldi M, Caroccia N, Gamberini C, Palacios-Baena ZR, Caponcello G, Morelli MC, Tamè M, Busutti M, Comai G, Potena L, Salvaterra E, Feltrin G, Cillo U, Gerosa G, Cananzi M, Piano S, Benetti E, Burra P, Loy M, Furian L, Zaza G, Onorati F, Carraro A, Gastaldon F, Nordio M, Kumar-Singh S, Abedini M, Boffetta P, Rodríguez-Baño J, Lazzarotto T, Viale P, Tacconelli E, On Behalf Of The Orchestra Study Group Workpackage

Microorganisms

2022 May 12

Hyperthermia Enhances Efficacy of Chemotherapeutic Agents in Pancreatic Cancer Cell Lines.
Maurici CE, Colenbier R, Wylleman B, Brancato L, van Zwol E, Van den Bossche J, Timmermans JP, Giovannetti E, Mori da Cunha MGMC, Bogers J

Biomolecules

2022 Apr 29

Identification of Potential Urinary Metabolite Biomarkers of Pseudomonas aeruginosa Ventilator-Associated Pneumonia.
Jongers B, Hotterbeekx A, Bielen K, Vervliet P, Boddaert J, Lammens C, Fransen E, Baggerman G, Covaci A, Goossens H, Malhotra-Kumar S, Jorens PG, Kumar-Singh S

Biomark Insights

2022 May 13

Fractionated irradiation of MCF7 breast cancer cells rewires a gene regulatory circuit towards a treatment-resistant stemness phenotype.
Inalegwu A, Cuypers B, Claesen J, Janssen A, Coolkens A, Baatout S, Laukens K, De Vos WH, Quintens R

Mol Oncol

2022 Jun 15

Oligodendroglia-derived extracellular vesicles activate autophagy via LC3B/BAG3 to protect against oxidative stress with an enhanced effect for HSPB8 enriched vesicles.
Van den Broek B, Wuyts C, Sisto A, Pintelon I, Timmermans JP, Somers V, Timmerman V, Hellings N, Irobi J

Cell Commun Signal

2022 May 5

TNF-α-Secreting Lung Tumor-Infiltrated Monocytes Play a Pivotal Role During Anti-PD-L1 Immunotherapy.
De Ridder K, Locy H, Piccioni E, Zuazo MI, Awad RM, Verhulst S, Van Bulck M, De Vlaeminck Y, Lecocq Q, Reijmen E, De Mey W, De Beck L, Ertveldt T, Pintelon I, Timmermans JP, Escors D, Keyaerts M, Breckpot K, Goyvaerts C

Front Immunol

2022 Apr 14

Susceptibility profiles and resistance genomics of Pseudomonas aeruginosa isolates from European ICUs participating in the ASPIRE-ICU trial.
Torrens G, van der Schalk TE, Cortes-Lara S, Timbermont L, Del Barrio-Tofiño E, Xavier BB, Zamorano L, Lammens C, Ali O, Ruzin A, Goossens H, Kumar-Singh S, Kluytmans J, Paling F, MacLean RC, Köhler T, López-Causapé C, Malhotra-Kumar S, Oliver A, ASPIRE-ICU study team

J Antimicrob Chemother

2022 Jun 29

Host Immunity Influences the Composition of Murine Gut Microbiota.
Van Averbeke V, Berkell M, Mysara M, Rodriguez-Ruiz JP, Xavier BB, De Winter FHR, Jongers B', Jairam RK, Hotterbeekx A, Goossens H, Cohen ES, Malhotra-Kumar S, Kumar-Singh S

Front Immunol

2022 Mar 15

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