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Antwerp Centre for Advanced Microscopy
High impact science through systematic and quantitative imaging
Publications
Dipeptidyl Peptidase 9 in Human Leukocytes: Novel Inhibitors Induce Caspase-1- and Gasdermin-Dependent Cell Death.
De Loose J, Mertens K, Filippi N, Corthaut S, Benramdane S, Sim Y, Van Rymenant Y, Claesen K, Vliegen G, Berg M, Gomard T, Caljon G, Pintelon I, Van Der Veken P, De Meester I
Eur J Immunol
2025 Jun
Altered muscle transcriptome as molecular basis of long-term muscle weakness in survivors from critical illness.
Uzun Ayar C, Güiza F, Derese I, Pauwels L, Vander Perre S, Pintelon I, Casaer M, Van Aerde N, Hermans G, Derde S, Kreiss L, Van den Berghe G, Vanhorebeek I
Intensive Care Med
2025 Jun 10
Altered liver sinusoidal endothelial cells in MASLD and their evolution following lanifibranor treatment.
Rautou PE, Chotkoe S, Biquard L, Wettstein G, van der Graaff D, Liu Y, De Man J, Casteleyn C, Thys S, De Vos WH, Bedossa P, Cooreman MP, Baudin M, Abitbol JL, Huot-Marchand P, Dzen L, Albuquerque M, Broqua P, Junien JL, Vonghia L, Abdelmalek MF, Kwanten WJ, Paradis V, Francque SM
JHEP Rep
2025 Feb 22
Light-triggered nanocarriers for nucleic acid delivery.
Huang B, De Smedt SC, De Vos WH, Braeckmans K
Drug Deliv
2025 May 14
Partial normalization of hippocampal oscillatory activity during sleep in TgF344-AD rats coincides with increased cholinergic synapses at early-plaque stage of Alzheimer's disease.
Berg MVD, Heymans L, Toen D, Adhikari MA, Audekerke JV, Verschuuren M, Pintelon I, Vos WH, Linden AV, Verhoye M, Keliris GA
Acta Neuropathol Commun
2025 May 10
Aquaporin 4 modulation drives amyloid burden and cognitive abilities in an APPPS1 mouse model of Alzheimer's disease.
Manescu MD, Catalin B, Baldea I, Mateescu VO, Rosu GC, Boboc IKS, Istrate-Ofiteru AM, Liliac IM, Streba CT, Kumar-Singh S, Pirici D
Alzheimers Dement
2025 May
Nanosecond Laser Pulses Facilitating Efficient and Specific Cell Killing with Doxorubicin-Loaded Gold Nanoparticles Targeted to the Folate Receptor.
Goemaere I, Cielo A, Daniele R, Mastrotto F, De Smedt SC, De Vos WH, Salmaso S, Braeckmans K
Small Sci
2024 Dec 19
Human Transmembrane Serine Protease 2 (TMPRSS2) on Human Seminal Fluid Extracellular Vesicles Is Proteolytically Active.
Verhulst E, De Bruyn M, Berckmans P, Sim Y, Augustyns K, Pintelon I, Berg M, Van Wielendaele P, Lambeir AM, Sterckx YG, Nelissen I, De Meester I
J Extracell Vesicles
2025 Mar
Quasi-species prevalence and clinical impact of evolving SARS-CoV-2 lineages in European COVID-19 cohorts, January 2020 to February 2022.
Berkell M, Górska A, Smet M, Bachelet D, Gentilotti E, Guedes M, Franco-Yusti AM, Mazzaferri F, Forero EL, Matheeussen V, Visseaux B, Palacios-Baena ZR, Caroccia N, Florence AM, Charpentier C, van Leer C, Giannella M, Friedrich AW, Rodríguez-Baño J, Ghosn J, ORCHESTRA working group, Kumar-Singh S, Laouénan C, Tacconelli E, Malhotra-Kumar S, Members of the ORCHESTRA working group
Euro Surveill
2025 Mar
A human-specific, concerted repression of microcephaly genes contributes to radiation-induced growth defects in cortical organoids.
Ribeiro JH, Etlioglu E, Buset J, Janssen A, Puype H, Berden L, Mbouombouo Mfossa AC, De Vos WH, Vermeirssen V, Baatout S, Rajan N, Quintens R
iScience
2025 Jan 20
Unbiased identification of cell identity in dense mixed neural cultures.
De Beuckeleer S, Van De Looverbosch T, Van Den Daele J, Ponsaerts P, De Vos WH
Elife
2025 Jan 17
Protocol for fecal microbiota transplantation: A microaerophilic approach for mice housed in a specific pathogen-free facility.
Wouters S, Moors H, Verslegers M, Leys N, Malhotra-Kumar S, Kumar-Singh S, Mysara M
STAR Protoc
2025 Jan 7
Tracing carriage, acquisition, and transmission of ESBL-producing Escherichia coli over two years in a tertiary care hospital.
Nguyen MN, Gladstone BP, De Angelis G, Biggel M, Xavier BB, Lammens C, Lin Q, Van Puyvelde S, Goossens H, Kumar-Singh S, Glupczynski Y, Carmeli Y, Tacconelli E, Malhotra-Kumar S, SATURN WP1, 4, 5 study groups
Genome Med
2024 Dec 20
Proximity adjusted centroid mapping for accurate detection of nuclei in dense 3D cell systems.
Van De Looverbosch T, De Beuckeleer S, De Smet F, Sijbers J, De Vos WH
Comput Biol Med
2024 Dec 17
An agarose fluidic chip for high-throughput in toto organoid imaging.
De Beuckeleer S, Vanhooydonck A, Van Den Daele J, Van De Looverbosch T, Asselbergh B, Kim H, Campsteijn C, Ponsaerts P, Watts R, De Vos WH
Lab Chip
2025 Jan 14
Single-cell analysis of osmoregulation reveals heterogeneity of aquaporin 4 functionality in human astrocytes.
Steenberghen H, Beuckeleer S, Hellings N, Somers V, Breedam EV, Ponsaerts P, Nuydens R, Maurin H, Larsen PH, De Vos WH
Cytometry A
2024 Nov 6
Evolution of aberrant brain-wide spatiotemporal dynamics of resting-state networks in a Huntington's disease mouse model.
Vasilkovska T, Verschuuren M, Pustina D, van den Berg M, Van Audekerke J, Pintelon I, Cachope R, De Vos WH, Van der Linden A, Adhikari MH, Verhoye M
Clin Transl Med
2024 Oct
Calciprotein particles induce arterial stiffening ex vivo and impair vascular cell function.
Neutel CHG, Wesley CD, van Loo C, Civati C, Mertens F, Zurek M, Verhulst A, Pintelon I, De Vos WH, Spronck B, Roth L, De Meyer GRY, Martinet W, Guns PJ
Commun Biol
2024 Oct 2
Varicella-zoster virus recapitulates its immune evasive behaviour in matured hiPSC-derived neurospheroids.
Govaerts J, Van Breedam E, De Beuckeleer S, Goethals C, D'Incal CP, Di Stefano J, Van Calster S, Buyle-Huybrecht T, Boeren M, De Reu H, Paludan SR, Thiry M, Lebrun M, Sadzot-Delvaux C, Motaln H, Rogelj B, Van Weyenbergh J, De Vos WH, Vanden Berghe W, Ogunjimi B, Delputte P, Ponsaerts P
Front Immunol
2024 Sep 16
Chemosensory assessment and impact on quality of life in neurosensorial cluster of the post COVID 19 syndrome.
Gentilotti E, Gorska A, Cecchini MP, Mirandola M, Meroi M, De Nardo P, Sartori A, De Toffoli CK, Kumar-Singh S, Zanusso G, Monaco S, Tacconelli E, ORCHESTRA-UNIVR Study Group
Sci Rep
2024 Sep 9
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