Antwerp Centre for Advanced Microscopy

High impact science through systematic and quantitative imaging

Publications

Four-dimensional telomere analysis in recordings of living human cells acquired with controlled light exposure microscopy.

De Vos WH, Joss GH, Haffmans W, Hoebe RA, Manders EM, Van Oostveldt P

J Microsc

2010 Jun 1

https://doi.org/10.1111/j.1365-2818.2009.03350.x

Neurotrophin-4 dependency of intraepithelial vagal sensory nerve terminals that selectively contact pulmonary NEBs in mice.

Oztay F, Brouns I, Pintelon I, Raab M, Neuhuber W, Timmermans JP, Adriaensen D

Histol Histopathol

2010 Aug

https://doi.org/10.14670/HH-25.975

Identification of three novel genetic variants in the melanocortin-3 receptor of obese children.

Zegers D, Beckers S, de Freitas F, Peeters AV, Mertens IL, Verhulst SL, Rooman RP, Timmermans JP, Desager KN, Massa G, Van Gaal LF, Van Hul W

Obesity (Silver Spring)

2010 Jun 10

https://doi.org/10.1038/oby.2010.127

Mutant HSPB8 causes motor neuron-specific neurite degeneration.

Irobi J, Almeida-Souza L, Asselbergh B, De Winter V, Goethals S, Dierick I, Krishnan J, Timmermans JP, Robberecht W, De Jonghe P, Van Den Bosch L, Janssens S, Timmerman V

Hum Mol Genet

2010 Jun 10

https://doi.org/10.1093/hmg/ddq234

FUS pathology defines the majority of tau- and TDP-43-negative frontotemporal lobar degeneration.

Urwin H, Josephs KA, Rohrer JD, Mackenzie IR, Neumann M, Authier A, Seelaar H, Van Swieten JC, Brown JM, Johannsen P, Nielsen JE, Holm IE, FReJA Consortium, Dickson DW, Rademakers R, Graff-Radford NR, Parisi JE, Petersen RC, Hatanpaa KJ, White CL 3rd, Weiner MF, Geser F, Van Deerlin VM, Trojanowski JQ, Miller BL, Seeley WW, van der Zee J, Kumar-Singh S, Engelborghs S, De Deyn PP, Van Broeckhoven C, Bigio EH, Deng HX, Halliday GM, Kril JJ, Munoz DG, Mann DM, Pickering-Brown SM, Doodeman V, Adamson G, Ghazi-Noori S, Fisher EM, Holton JL, Revesz T, Rossor MN, Collinge J, Mead S, Isaacs AM

Acta Neuropathol

2010 May 20

https://doi.org/10.1007/s00401-010-0698-6

Identification of 2 Loci at chromosomes 9 and 14 in a multiplex family with frontotemporal lobar degeneration and amyotrophic lateral sclerosis.

Gijselinck I, Engelborghs S, Maes G, Cuijt I, Peeters K, Mattheijssens M, Joris G, Cras P, Martin JJ, De Deyn PP, Kumar-Singh S, Van Broeckhoven C, Cruts M

Arch Neurol

2010 May

https://doi.org/10.1001/archneurol.2010.82

Current perspective of pathophysiological and interventional effects on endothelial progenitor cell biology: focus on PI3K/AKT/eNOS pathway.

Everaert BR, Van Craenenbroeck EM, Hoymans VY, Haine SE, Van Nassauw L, Conraads VM, Timmermans JP, Vrints CJ

Int J Cardiol

2010 May 4

https://doi.org/10.1016/j.ijcard.2010.04.018

Impairment of intestinal barrier and secretory function as well as egg excretion during intestinal schistosomiasis occur independently of mouse mast cell protease-1.

Rychter JW, Van Nassauw L, Brown JK, Van Marck E, Knight PA, Miller HR, Kroese AB, Timmermans JP

Parasite Immunol

2010 Apr

https://doi.org/10.1111/j.1365-3024.2009.01182.x

Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions.

Van Deerlin VM, Sleiman PM, Martinez-Lage M, Chen-Plotkin A, Wang LS, Graff-Radford NR, Dickson DW, Rademakers R, Boeve BF, Grossman M, Arnold SE, Mann DM, Pickering-Brown SM, Seelaar H, Heutink P, van Swieten JC, Murrell JR, Ghetti B, Spina S, Grafman J, Hodges J, Spillantini MG, Gilman S, Lieberman AP, Kaye JA, Woltjer RL, Bigio EH, Mesulam M, Al-Sarraj S, Troakes C, Rosenberg RN, White CL 3rd, Ferrer I, Lladó A, Neumann M, Kretzschmar HA, Hulette CM, Welsh-Bohmer KA, Miller BL, Alzualde A, Lopez de Munain A, McKee AC, Gearing M, Levey AI, Lah JJ, Hardy J, Rohrer JD, Lashley T, Mackenzie IR, Feldman HH, Hamilton RL, Dekosky ST, van der Zee J, Kumar-Singh S, Van Broeckhoven C, Mayeux R, Vonsattel JP, Troncoso JC, Kril JJ, Kwok JB, Halliday GM, Bird TD, Ince PG, Shaw PJ, Cairns NJ, Morris JC, McLean CA, DeCarli C, Ellis WG, Freeman SH, Frosch MP, Growdon JH, Perl DP, Sano M, Bennett DA, Schneider JA, Beach TG, Reiman EM, Woodruff BK, Cummings J, Vinters HV, Miller CA, Chui HC, Alafuzoff I, Hartikainen P, Seilhean D, Galasko D, Masliah E, Cotman CW, Tuñón MT, Martínez MC, Munoz DG, Carroll SL, Marson D, Riederer PF, Bogdanovic N, Schellenberg GD, Hakonarson H, Trojanowski JQ, Lee VM

Nat Genet

2010 Feb 14

https://doi.org/10.1038/ng.536

TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration.

Wils H, Kleinberger G, Janssens J, Pereson S, Joris G, Cuijt I, Smits V, Ceuterick-de Groote C, Van Broeckhoven C, Kumar-Singh S

Proc Natl Acad Sci U S A

2010 Feb 3

https://doi.org/10.1073/pnas.0912417107

Development of rat tibia innervation: colocalization of autonomic nerve fiber markers with growth-associated protein 43.

Gajda M, Litwin JA, Tabarowski Z, Zagólski O, Cichocki T, Timmermans JP, Adriaensen D

Cells Tissues Organs

2010 Jan 14

https://doi.org/10.1159/000276591

Medium-mediated DNA repair response after ionizing radiation is correlated with the increase of specific cytokines in human fibroblasts.

Dieriks B, De Vos WH, Derradji H, Baatout S, Van Oostveldt P

Mutat Res

2010 Jan 18

https://doi.org/10.1016/j.mrfmmm.2010.01.011

Increased plasticity of the nuclear envelope and hypermobility of telomeres due to the loss of A-type lamins.

De Vos WH, Houben F, Hoebe RA, Hennekam R, van Engelen B, Manders EM, Ramaekers FC, Broers JL, Van Oostveldt P

Biochim Biophys Acta

2010 Jan 14

https://doi.org/10.1016/j.bbagen.2010.01.002

Blebbistatin inhibits contraction and accelerates migration in mouse hepatic stellate cells.

Liu Z, van Grunsven LA, Van Rossen E, Schroyen B, Timmermans JP, Geerts A, Reynaert H

Br J Pharmacol

2009 Dec 18

https://doi.org/10.1111/j.1476-5381.2009.00477.x

Fractal analysis of amyloid plaques in Alzheimer's disease patients and mouse models.

Pirici D, Van Cauwenberghe C, Van Broeckhoven C, Kumar-Singh S

Neurobiol Aging

2009 Dec 16

https://doi.org/10.1016/j.neurobiolaging.2009.10.010

Folding properties of the hepatitis B core as a carrier protein for vaccination research.

Janssens ME, Geysen D, Broos K, De Goeyse I, Robbens J, Van Petegem F, Timmermans JP, Guisez Y

Amino Acids

2009 Dec 3

https://doi.org/10.1007/s00726-009-0365-1

Neurodegeneration and neuroplasticity in the peripheral and central nervous system.

Pochet R, Timmermans JP

Anat Rec (Hoboken)

2009 Dec

https://doi.org/10.1002/ar.21075

Nomenclature and nosology for neuropathologic subtypes of frontotemporal lobar degeneration: an update.

Mackenzie IR, Neumann M, Bigio EH, Cairns NJ, Alafuzoff I, Kril J, Kovacs GG, Ghetti B, Halliday G, Holm IE, Ince PG, Kamphorst W, Revesz T, Rozemuller AJ, Kumar-Singh S, Akiyama H, Baborie A, Spina S, Dickson DW, Trojanowski JQ, Mann DM

Acta Neuropathol

2009 Nov 19

https://doi.org/10.1007/s00401-009-0612-2

The rate-dependent biophysical properties of the LQT1 H258R mutant are counteracted by a dominant negative effect on channel trafficking.

Labro AJ, Boulet IR, Timmermans JP, Ottschytsch N, Snyders DJ

J Mol Cell Cardiol

2009 Nov 11

https://doi.org/10.1016/j.yjmcc.2009.10.027

MRI visualization of endogenous neural progenitor cell migration along the RMS in the adult mouse brain: validation of various MPIO labeling strategies.

Vreys R, Vande Velde G, Krylychkina O, Vellema M, Verhoye M, Timmermans JP, Baekelandt V, Van der Linden A

Neuroimage

2009 Oct 19

https://doi.org/10.1016/j.neuroimage.2009.10.034

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