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Antwerp Centre for Advanced Microscopy
High impact science through systematic and quantitative imaging
Publications
Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions.
Van Deerlin VM, Sleiman PM, Martinez-Lage M, Chen-Plotkin A, Wang LS, Graff-Radford NR, Dickson DW, Rademakers R, Boeve BF, Grossman M, Arnold SE, Mann DM, Pickering-Brown SM, Seelaar H, Heutink P, van Swieten JC, Murrell JR, Ghetti B, Spina S, Grafman J, Hodges J, Spillantini MG, Gilman S, Lieberman AP, Kaye JA, Woltjer RL, Bigio EH, Mesulam M, Al-Sarraj S, Troakes C, Rosenberg RN, White CL 3rd, Ferrer I, Lladó A, Neumann M, Kretzschmar HA, Hulette CM, Welsh-Bohmer KA, Miller BL, Alzualde A, Lopez de Munain A, McKee AC, Gearing M, Levey AI, Lah JJ, Hardy J, Rohrer JD, Lashley T, Mackenzie IR, Feldman HH, Hamilton RL, Dekosky ST, van der Zee J, Kumar-Singh S, Van Broeckhoven C, Mayeux R, Vonsattel JP, Troncoso JC, Kril JJ, Kwok JB, Halliday GM, Bird TD, Ince PG, Shaw PJ, Cairns NJ, Morris JC, McLean CA, DeCarli C, Ellis WG, Freeman SH, Frosch MP, Growdon JH, Perl DP, Sano M, Bennett DA, Schneider JA, Beach TG, Reiman EM, Woodruff BK, Cummings J, Vinters HV, Miller CA, Chui HC, Alafuzoff I, Hartikainen P, Seilhean D, Galasko D, Masliah E, Cotman CW, Tuñón MT, Martínez MC, Munoz DG, Carroll SL, Marson D, Riederer PF, Bogdanovic N, Schellenberg GD, Hakonarson H, Trojanowski JQ, Lee VM
Nat Genet
2010 Feb 14
TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration.
Wils H, Kleinberger G, Janssens J, Pereson S, Joris G, Cuijt I, Smits V, Ceuterick-de Groote C, Van Broeckhoven C, Kumar-Singh S
Proc Natl Acad Sci U S A
2010 Feb 3
Development of rat tibia innervation: colocalization of autonomic nerve fiber markers with growth-associated protein 43.
Gajda M, Litwin JA, Tabarowski Z, Zagólski O, Cichocki T, Timmermans JP, Adriaensen D
Cells Tissues Organs
2010 Jan 14
Medium-mediated DNA repair response after ionizing radiation is correlated with the increase of specific cytokines in human fibroblasts.
Dieriks B, De Vos WH, Derradji H, Baatout S, Van Oostveldt P
Mutat Res
2010 Jan 18
Increased plasticity of the nuclear envelope and hypermobility of telomeres due to the loss of A-type lamins.
De Vos WH, Houben F, Hoebe RA, Hennekam R, van Engelen B, Manders EM, Ramaekers FC, Broers JL, Van Oostveldt P
Biochim Biophys Acta
2010 Jan 14
Blebbistatin inhibits contraction and accelerates migration in mouse hepatic stellate cells.
Liu Z, van Grunsven LA, Van Rossen E, Schroyen B, Timmermans JP, Geerts A, Reynaert H
Br J Pharmacol
2009 Dec 18
Fractal analysis of amyloid plaques in Alzheimer's disease patients and mouse models.
Pirici D, Van Cauwenberghe C, Van Broeckhoven C, Kumar-Singh S
Neurobiol Aging
2009 Dec 16
Folding properties of the hepatitis B core as a carrier protein for vaccination research.
Janssens ME, Geysen D, Broos K, De Goeyse I, Robbens J, Van Petegem F, Timmermans JP, Guisez Y
Amino Acids
2009 Dec 3
Neurodegeneration and neuroplasticity in the peripheral and central nervous system.
Pochet R, Timmermans JP
Anat Rec (Hoboken)
2009 Dec
Nomenclature and nosology for neuropathologic subtypes of frontotemporal lobar degeneration: an update.
Mackenzie IR, Neumann M, Bigio EH, Cairns NJ, Alafuzoff I, Kril J, Kovacs GG, Ghetti B, Halliday G, Holm IE, Ince PG, Kamphorst W, Revesz T, Rozemuller AJ, Kumar-Singh S, Akiyama H, Baborie A, Spina S, Dickson DW, Trojanowski JQ, Mann DM
Acta Neuropathol
2009 Nov 19
The rate-dependent biophysical properties of the LQT1 H258R mutant are counteracted by a dominant negative effect on channel trafficking.
Labro AJ, Boulet IR, Timmermans JP, Ottschytsch N, Snyders DJ
J Mol Cell Cardiol
2009 Nov 11
MRI visualization of endogenous neural progenitor cell migration along the RMS in the adult mouse brain: validation of various MPIO labeling strategies.
Vreys R, Vande Velde G, Krylychkina O, Vellema M, Verhoye M, Timmermans JP, Baekelandt V, Van der Linden A
Neuroimage
2009 Oct 19
High content image cytometry in the context of subnuclear organization.
De Vos WH, Van Neste L, Dieriks B, Joss GH, Van Oostveldt P
Cytometry A
2010 Jan
Conserved negative charges in the N-terminal tetramerization domain mediate efficient assembly of Kv2.1 and Kv2.1/Kv6.4 channels.
Bocksteins E, Labro AJ, Mayeur E, Bruyns T, Timmermans JP, Adriaensen D, Snyders DJ
J Biol Chem
2009 Aug 28
Progranulin expression correlates with dense-core amyloid plaque burden in Alzheimer disease mouse models.
Pereson S, Wils H, Kleinberger G, McGowan E, Vandewoestyne M, Van Broeck B, Joris G, Cuijt I, Deforce D, Hutton M, Van Broeckhoven C, Kumar-Singh S
J Pathol
2009 Oct
Voltage-gated delayed rectifier K v 1-subunits may serve as distinctive markers for enteroglial cells with different phenotypes in the murine ileum.
Costagliola A, Van Nassauw L, Snyders D, Adriaensen D, Timmermans JP
Neurosci Lett
2009 Jun 21
In vitro susceptibilities of Leishmania donovani promastigote and amastigote stages to antileishmanial reference drugs: practical relevance of stage-specific differences.
Vermeersch M, da Luz RI, Toté K, Timmermans JP, Cos P, Maes L
Antimicrob Agents Chemother
2009 Jun 22
Somatostatin modulates mast cell-induced responses in murine spinal neurons and satellite cells.
Van Op den bosch J, Van Nassauw L, Van Marck E, Timmermans JP
Am J Physiol Gastrointest Liver Physiol
2009 May 28
Hereditary and sporadic forms of abeta-cerebrovascular amyloidosis and relevant transgenic mouse models.
Kumar-Singh S
Int J Mol Sci
2009 Apr 23
Involvement of afferent neurons in the pathogenesis of endotoxin-induced ileus in mice: role of CGRP and TRPV1 receptors.
De Winter BY, Bredenoord AJ, Van Nassauw L, De Man JG, De Schepper HU, Timmermans JP, Pelckmans PA
Eur J Pharmacol
2009 May 13
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