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Antwerp Centre for Advanced Microscopy
High impact science through systematic and quantitative imaging
Publications
Immunostimulatory activity of inactivated environmental Bacillus isolates and their endospores.
Dekeukeleire M, Vandenheuvel D, Khondee T, Delanghe L, Van Rillaer T, Thys S, Timmermans JP, Lebeer S, Spacova I
Sci Rep
2025 Aug 20
Biophysical analysis of an oligomerization-attenuated variant of the Leishmania donovani dynamin-1-like protein.
Wuyts E, Sundaramoorthy R, Tulloch L, Monsieurs P, Eadsforth TC, Pintelon I, Timmermans JP, Dujardin JC, Domagalska MA, Caljon G, De Rycker M, Postis VLG, Wyllie S, Sterckx YG
Mol Biochem Parasitol
2025 Aug 14
In-depth study of gastrointestinal motility, intestinal barrier function and secretory function in an irritable bowel syndrome post-inflammatory rat model.
Hanning N, Verboven R, Smet A, Timmermans JP, De Man JG, De Winter BY
Eur J Pharmacol
2025 Jul 24
Fibroblast activation protein on human natural killer cells: insights from natural killer cell activation and crosstalk with cancer-associated fibroblasts.
Van Rymenant Y, de Groot A, Dirkx L, Verhulst E, De Loose J, Pintelon I, Verhezen T, De Waele J, Thys S, De Wever O, Tanc M, Caljon G, Van der Veken P, De Meester I
J Leukoc Biol
2025 Jul 9
Drivers of quasispecies development in SARS-CoV-2 and implications for emergent variants and COVID-19.
Smet M, Berkell M, Górska A, Tacconelli E, Kumar-Singh S, Malhotra-Kumar S
Virology
2025 May 26
Dipeptidyl Peptidase 9 in Human Leukocytes: Novel Inhibitors Induce Caspase-1- and Gasdermin-Dependent Cell Death.
De Loose J, Mertens K, Filippi N, Corthaut S, Benramdane S, Sim Y, Van Rymenant Y, Claesen K, Vliegen G, Berg M, Gomard T, Caljon G, Pintelon I, Van Der Veken P, De Meester I
Eur J Immunol
2025 Jun
Altered muscle transcriptome as molecular basis of long-term muscle weakness in survivors from critical illness.
Uzun Ayar C, Güiza F, Derese I, Pauwels L, Vander Perre S, Pintelon I, Casaer M, Van Aerde N, Hermans G, Derde S, Kreiss L, Van den Berghe G, Vanhorebeek I
Intensive Care Med
2025 Jun 10
Altered liver sinusoidal endothelial cells in MASLD and their evolution following lanifibranor treatment.
Rautou PE, Chotkoe S, Biquard L, Wettstein G, van der Graaff D, Liu Y, De Man J, Casteleyn C, Thys S, De Vos WH, Bedossa P, Cooreman MP, Baudin M, Abitbol JL, Huot-Marchand P, Dzen L, Albuquerque M, Broqua P, Junien JL, Vonghia L, Abdelmalek MF, Kwanten WJ, Paradis V, Francque SM
JHEP Rep
2025 Feb 22
Light-triggered nanocarriers for nucleic acid delivery.
Huang B, De Smedt SC, De Vos WH, Braeckmans K
Drug Deliv
2025 May 14
Partial normalization of hippocampal oscillatory activity during sleep in TgF344-AD rats coincides with increased cholinergic synapses at early-plaque stage of Alzheimer's disease.
Berg MVD, Heymans L, Toen D, Adhikari MA, Audekerke JV, Verschuuren M, Pintelon I, Vos WH, Linden AV, Verhoye M, Keliris GA
Acta Neuropathol Commun
2025 May 10
Aquaporin 4 modulation drives amyloid burden and cognitive abilities in an APPPS1 mouse model of Alzheimer's disease.
Manescu MD, Catalin B, Baldea I, Mateescu VO, Rosu GC, Boboc IKS, Istrate-Ofiteru AM, Liliac IM, Streba CT, Kumar-Singh S, Pirici D
Alzheimers Dement
2025 May
Nanosecond Laser Pulses Facilitating Efficient and Specific Cell Killing with Doxorubicin-Loaded Gold Nanoparticles Targeted to the Folate Receptor.
Goemaere I, Cielo A, Daniele R, Mastrotto F, De Smedt SC, De Vos WH, Salmaso S, Braeckmans K
Small Sci
2024 Dec 19
Human Transmembrane Serine Protease 2 (TMPRSS2) on Human Seminal Fluid Extracellular Vesicles Is Proteolytically Active.
Verhulst E, De Bruyn M, Berckmans P, Sim Y, Augustyns K, Pintelon I, Berg M, Van Wielendaele P, Lambeir AM, Sterckx YG, Nelissen I, De Meester I
J Extracell Vesicles
2025 Mar
Quasi-species prevalence and clinical impact of evolving SARS-CoV-2 lineages in European COVID-19 cohorts, January 2020 to February 2022.
Berkell M, Górska A, Smet M, Bachelet D, Gentilotti E, Guedes M, Franco-Yusti AM, Mazzaferri F, Forero EL, Matheeussen V, Visseaux B, Palacios-Baena ZR, Caroccia N, Florence AM, Charpentier C, van Leer C, Giannella M, Friedrich AW, Rodríguez-Baño J, Ghosn J, ORCHESTRA working group, Kumar-Singh S, Laouénan C, Tacconelli E, Malhotra-Kumar S, Members of the ORCHESTRA working group
Euro Surveill
2025 Mar
A human-specific, concerted repression of microcephaly genes contributes to radiation-induced growth defects in cortical organoids.
Ribeiro JH, Etlioglu E, Buset J, Janssen A, Puype H, Berden L, Mbouombouo Mfossa AC, De Vos WH, Vermeirssen V, Baatout S, Rajan N, Quintens R
iScience
2025 Jan 20
Unbiased identification of cell identity in dense mixed neural cultures.
De Beuckeleer S, Van De Looverbosch T, Van Den Daele J, Ponsaerts P, De Vos WH
Elife
2025 Jan 17
Protocol for fecal microbiota transplantation: A microaerophilic approach for mice housed in a specific pathogen-free facility.
Wouters S, Moors H, Verslegers M, Leys N, Malhotra-Kumar S, Kumar-Singh S, Mysara M
STAR Protoc
2025 Jan 7
Tracing carriage, acquisition, and transmission of ESBL-producing Escherichia coli over two years in a tertiary care hospital.
Nguyen MN, Gladstone BP, De Angelis G, Biggel M, Xavier BB, Lammens C, Lin Q, Van Puyvelde S, Goossens H, Kumar-Singh S, Glupczynski Y, Carmeli Y, Tacconelli E, Malhotra-Kumar S, SATURN WP1, 4, 5 study groups
Genome Med
2024 Dec 20
Proximity adjusted centroid mapping for accurate detection of nuclei in dense 3D cell systems.
Van De Looverbosch T, De Beuckeleer S, De Smet F, Sijbers J, De Vos WH
Comput Biol Med
2024 Dec 17
An agarose fluidic chip for high-throughput in toto organoid imaging.
De Beuckeleer S, Vanhooydonck A, Van Den Daele J, Van De Looverbosch T, Asselbergh B, Kim H, Campsteijn C, Ponsaerts P, Watts R, De Vos WH
Lab Chip
2025 Jan 14
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